Welcome to M⁴: Medicine, Mystery, Mayhem... and Sometimes Murder!
M⁴: Medicine, Mystery, Mayhem... and Sometimes Murder

M⁴: Medicine, Mystery, Mayhem... and Sometimes Murder

Hosted by two seasoned RNs with over 45 years of combined experience and a friendship nearly as long, the M⁴ Podcast dives into the strange, shocking, and sometimes spine-chilling side of medicine. Each episode explores real cases, bizarre conditions, historical medical mysteries, and the occasional true crime, with expert insight, unfiltered commentary, and a touch of gallows humor.

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Recent Episodes

Jan. 13, 2026

Memories

Did Nelson Mandela really die in prison? Was it Berenstain or Berenstein Bears? And why do so many of us remember the exact same things… wrong? In this episode, Andrea and Crystal unravel the Mandela Effect, the bizarre pheno...
Jan. 6, 2026

Disappear

Some disappearances are mysterious. Others are tragic. A rare few feel like they break the rules of reality itself . In this episode of Medicine, Mystery, Mayhem & Murder (M⁴) , Andrea and Crystal explore seven cases where pe...
Dec. 30, 2025

Once Bitten, Twice Shy

For nearly seven years, Cindy James reported being stalked. She called police again and again. She documented threats, break-ins, and assaults. On more than one occasion, she was found drugged, bound, injured. Every time, the...
Dec. 24, 2025

Have a Holly Jolly Christmas

Christmas means different things to people around the world. This week, Andrea and Crystal take listeners on a festive journey across cultures, exploring the unique traditions, customs, and celebrations that make the holiday ...
Dec. 17, 2025

Toxic

Gloria Ramirez arrived at Riverside General Hospital in cardiac arrest—but what happened next defied medical logic. During resuscitation, multiple healthcare workers became ill, some losing consciousness. Reports of an ammoni...
Dec. 9, 2025

Got Me Feeling So Crazy Right Now

When journalist Susannah Cahalan suddenly unraveled—losing her memory, her behavior, and even her sense of self—doctors were baffled. In this episode, Andrea and Crystal dive into the terrifying medical mystery behind Brain o...